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NCAM-180 is a structural molecule that mediates cell-cell adhesion, resulting in tissue stabilization. It has been proposed as a tumor suppressor in colon carcinoma.
As in the development of many human cancers, in a transgenic mouse model of β-cell carcinogenesis (Rip1Tag2), expression of neural cell adhesion molecule (NCAM) changes from the 120-kDa isoform ...
et al. Neural cell adhesion molecule (NCAM) promotes the differentiation of hippocampal precursor cells to a neuronal lineage, especially to a glutamatergic neural cell type.
During cell adhesion, the extracellular domain binds to another cell adhesion molecule. In response, the transmembrane region rearranges the structure of the intracellular domain—a process ...
Over the years, deficits in neural cell adhesion molecules have been implicated in schizophrenia and other psychiatric disorders. One adhesion molecule, neurexin, ...
The team studied a protein in the brain called neural cell adhesion molecule 2, or NCAM2 -- one of a family of molecules that physically connects the membranes of synapses and help stabilise these ...
A twisted cell-cell adhesion molecule complex structure revealed by single-molecule fluorescence microscopy and high-speed atomic force microscopy. National Institutes of Natural Sciences.
A small molecule called ISRIB that was identified at UC San Francisco can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research has found. ISRIB ...
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