Inhibikase (IKT) pivots to IkT-001Pro for PAH amid competition like Merck’s sotatercept. Backed by $97.5M, results will ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

A new study published in The New England Journal of Medicine showed that for high-risk patients with pulmonary arterial ...

Weak: only small or nonrandomized trials available; Unknown: not enough data to determine benefit. ERA: Endothelin receptor antagonist; PDE5: Phosphodiesterase type 5; PH: Pulmonary hypertension.

Key findings showed remodeling effects: Firstly ... aiming to reduce wall stress and increase vascular resistance. These changes indicate an antihypertensive response, reducing the effects of ...

Center for Pulmonary Vascular Biology and Medicine ... In pulmonary hypertension, however, this partnership turns lethal. PAAFs start remodeling their external environment and secrete signals that ...

PASMC and PAAF undergo distinct phenotypic shifts during pulmonary vascular remodeling, with limited shared features, such as reduced mitochondrial content and hyperpolarization. IPAH-PASMC exhibit ...

1 Department of Vascular Surgery, China-Japan Union Hospital, Jilin University, Changchun, China 2 College of Basic Medical Sciences, Jilin University, Changchun, China The role of oxidative stress in ...

A recent publication in the International Journal of Cardiology, Pulmonary artery denervation in pulmonary hypertension: A comprehensive meta-analysis, has shed light on the potential of pulmonary ...

It just makes me feel really grounded in my body." The two-time Oscar winner excitedly revealed that she was remodeling a part of her home into a gym. "I'm actually building a gym in my garage ...