This valuable study proposes a novel rapid-entry mechanism of S. aureus that involves the rapid release of calcium from lysosomes. The strength of the paper lies in a very interesting hypothesis; what ...

Major differences among the main spinal V1 inhibitory interneuron subgroups were revealed based on neurogenesis, circuit placement, and motoneuron targeting, and Foxp2-V1 interneurons were identified ...

Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake.

During rest and sleep, memory traces replay in the brain. The dialogue between brain regions during replay is thought to stabilize labile memory traces for long-term storage. However, because replay ...

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States ...

The manuscript by Sayeed et al. uses a comprehensive series of multi-omics approaches to demonstrate that late-stage human cytomegalovirus (HCMV) infection leads to a marked disruption of TEAD1 ...

This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

This study investigates the molecular mechanisms underlying chronic pain-related memory impairment by focusing on S1P/S1PR1 signaling in the dentate gyrus (DG) of the hippocampus. Through behavioral ...

Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...

Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, Columbus, USA ...