Objectives To provide updated estimates of the global burden of oesophageal and gastric cancer by subsite and type. Methods Using data from population-based cancer registries, proportions of ...

Correspondence to Dr Gert Van Assche, Division of Gastroenterology, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium; gert.vanassche{at}uzleuven.be Data in a prospectively followed ...

Gene Expression Unit, Department of Molecular Cell Biology, Katholieke Universiteit Leuven, Leuven, Belgium Background and aims: Infliximab is an effective treatment for ulcerative colitis with over ...

Objective High-fat diet (HFD)-induced metabolic disorders can lead to impaired sperm production. We aim to investigate if HFD-induced gut microbiota dysbiosis can functionally influence ...

Li M, Xu C, Shi J, et al.et al Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway.Gut 2018;67:2169–80. This article has been ...

Correspondence to Professor Peter R Gibson, Department of Gastroenterology, Monash University and Alfred Health, Melbourne, VIC 3004, Australia; Peter.gibson{at}monash.edu Reasons behind such ...

Objective A decade of microbiome studies has linked IBD to an alteration in the gut microbial community of genetically predisposed subjects. However, existing profiles of gut microbiome dysbiosis in ...

Objective Follow-up studies have shown that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident diabetes, but currently, it is uncertain whether this risk ...

Objective Over half of patients with IBS have either diarrhoea (IBS-D) or a mixed stool pattern (IBS-M). The relative efficacy of licenced pharmacological therapies is unclear in the absence of ...

The goal of this review is to describe barrier function of the intestine, the structure of the tight junction, methods to evaluate intestinal permeability, and most importantly the relevance of ...

1 Department of Hepatology, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium 2 Morphology and Molecular Pathology, University Hospital Gasthuisberg, KU Leuven, Leuven, Belgium 3 Medical ...

Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn’s disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is among the largest ...