Genes Involved in Spinal Muscular Atrophy
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Genes Involved in Spinal Muscular Atrophy
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Cause of SMA
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Genes Involved With Spinal Muscular Atrophy
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Spinal Muscular Atrophy and the SMN2 Gene
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SMA is a hereditary condition, meaning it is passed down from parents to children. The most common form of SMA is caused by a defect in the SMN1 gene. This gene is responsible for producing the SMN protein, which is crucial for the survival of motor neurons. When the SMN1 gene is mutated, it can't produce enough SMN protein, leading to the degeneration and death of motor neurons. The loss of motor neurons in SMA causes progressive muscle weakness and atrophy. This can affect various muscles thro
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SMA is a hereditary condition, meaning it is passed down from parents to children. The most common form of SMA is caused by a defect in the SMN1 gene. This gene is responsible for producing the SMN protein, which is crucial for the survival of motor neurons. When the SMN1 gene is mutated, it can't produce enough SMN protein, leading to the degeneration and death of motor neurons. The loss of motor neurons in SMA causes progressive muscle weakness and atrophy. This can affect various muscles thro
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Some people may think spinal muscular atrophy (SMA) is always a fatal disease. Advances in SMA screening and innovation aim to improve outcomes in those diagnosed early in life, with the more rapidly progressing types of SMA. Watch to learn about #UnderstandingSMA. | Biogen
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Spinal muscular Atrophy (SMA) is a group of genetic diseases that cause muscle weakness and wasting (atrophy) due to the loss of specialized nerve cells called motor neurons. These motor neurons, located in the spinal cord and brainstem, are crucial for controlling voluntary muscle movements like walking, breathing, and swallowing. SMA is primarily caused by mutations in the SMN1 gene, which lead to a deficiency in the SMN protein, essential for motor neuron survival and function. Key aspects of
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