TONIGHT: Lester Holt anchors NBC Nightly News from Washington, D.C. after American Eagle Flight 5342 carrying 60 passengers and four crew members, collided midair with an Army helicopter near Reagan Washington National Airport | NBC Nightly News with Tom Llamas

Lester Holt signs off at the end of his first broadcast as anchor of #NBCNightlyNews | NBC Nightly News with Tom Llamas

Here's Tom Llamas with a preview of tonight's NBC Nightly News. Join us at 6:30 pm ET / 5:30 pm CT (check local listings). | NBC Nightly News with Tom Llamas

Gov. Cuomo responds to President Trump, who said he doesn't believe New York needs 30,000 ventilators. "I hope no one needs a ventilator," Cuomo told Lester Holt today. "But I don't operate on what I hope...I operate on the data..." Watch the interview tonight on Nightly News. | NBC Nightly News with Tom Llamas

17K views · 264 reactions | REMEMBERING JOHN LEWIS: Ava DuVernay tells Lester Holt what she learned from John Lewis while working with him on the film "Selma." "I'll miss him," she says. | NBC Nightly News with Tom Llamas | Facebook

TONIGHT: Lester Holt interviews Dr. Anthony Fauci as the US adds travel restrictions in response to the Omicron Covid-19 variant. We'll have the latest tonight on NBC Nightly News at 6:30 ET / 5:30 CT (check your local NBC station listings). Read more: https://nbcnews.to/3p4LxV5 | NBC Nightly News with Tom Llamas